Description: | The Young Mania Rating Scale (YMRS) is the most frequently used scale for assessing symptoms of mania in patients diagnosed with or being screened for bipolar disorder. The scale has 11 items and is based on the patient’s self-report of his or her condition over the previous 48 hours. |
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Disease States: | Bipolar disorder |
Validated Uses: | Screening, Symptom Severity |
Administration Method: | Clinician-report |
Time to administer: | 16–30 minutes |
Commonly used in: | Clinical Trials & Research |
Detailed Description: | The YMRS is an 11-item scale.1,7 Seven items are ranked on a scale of 0 to 4 (elevated mood, increased motor activity/energy, sexual interest, reduction in sleep, language/thought disorder, poor appearance, lack of insight).1,7 Four items are ranked on a scale of 0 to 8 (irritability, rate and amount of speech, thought content, disruptive/aggressive behavior).1,8 Intermediate or half point ratings can be assigned in patients for whom symptom severity falls between 2 defined anchor points.1,7 The total score ranges from 0 (none) to 60 (most severe).7 A YMRS score > 20 is commonly used as inclusion criteria in clinical trials for bipolar disorder.2 When used for tracking symptom progression over time, a difference of 6 to 7 points on the YMRS is thought to be clinically significant.2 |
Scale Validity: | Duplicate ratings of 35 patients with manic symptoms demonstrate that inter-rater reliability of the YMRS is high, ranging from 0.66 to 0.95 depending on the item.1 |
Alternative Versions: | The YMRS has been modified for use in pediatric and adolescent populations.8,9 A parent-report adaptation of the YMRS (commonly known as the P-YMRS) was designed to be completed by parents.8,9 |
Cited Limitations: | The YMRS is not comprehensive and does not evaluate all possible manifestations of mania.5 Some symptoms of mania that are not addressed include distractibility, increases in goal-directed activity, and excessive involvement in pleasurable yet risky activities.5 |
Footnotes:
Supporting references for the filters are as follows:
Disease States: Bipolar disorder1,2; Validated Uses: Screening,3 Symptom Severity1,4,5; Administration Method: Clinician-report1,3; Time to administer: 16–30 minutes1,5; Commonly used in: Clinical Trials & Research2,5,6,7
This resource is intended for educational purposes only and is intended for US healthcare professionals. Healthcare professionals should use independent medical judgment. All decisions regarding patient care must be handled by a healthcare professional and be made based on the unique needs of each patient.
ABBV-US-01580-MC, Version 1.0
Approved 04/2024
AbbVie Medical Affairs